Antidiarrheal potential of methanol extract of Combretum dolichopetalumand its fractions in wistar albino rats

The study investigated the antidiarrheal potential of methanol extract Combretum dolichopetalum and its solvent fractions. Leaves were extracted using as solvent. This was classified crude (MECD). further fractionated column chromatographic techniques to get various Castor oil used induce diarrhea in animals, following atropine plant extracts confirm any activity. Fecal excretion absorption/secretion ratio, enteropooling, small intestinal transit, glucose estimation, free fatty acid estimation fecal osmolarity employed serve biomarker. Result showed improvements all studied biomarkers compared negative control. worked similarly like standard drug atropine. So from result this study, it can be concluded that fractions contains compounds with potentials, justifies use ethnomedicine.